Marie Faughnan

Biographical Sketch
Dr. Faughnan is a clinician investigator performing clinical research in pulmonary disease. Dr. Faughnan also has a special interest in pulmonary vascular malformations and Hereditary Hemorrhagic Telangiectasia (HHT). Dr. Faughnan’s degrees include an MD from Université de Montréal and an MSc in Clinical Epidemiology from the University of Toronto. She is presently the Director of the HHT Program at St. Michael’s Hospital and University of Toronto and the Chair of the Scientific and Medical Advisory Board of the HHT Foundation International. Dr. Faughnan is also the Director of the Pulmonary Function Laboratory and Exercise Testing Laboratory at St. Michael’s Hospital.

Dr. Faughnan is currently leading studies in COPD, effects of air pollution, exercise testing outcomes in COPD and has developed a COPD Database at St. Michael’s Hospital. Other ongoing studies involve clinical diagnosis and outcomes for pulmonary arteriovenous malformations, impacts of genetic diagnosis for HHT and the elucidation of vascular mechanisms of disease in HHT.

University Appointments
Assistant Professor, Department of Medicine, University of Toronto

Hospital Appointments
Staff Physician, St. Michael’s Hospital
Associate Physician, Centre Hospitalier de l’Université de Montréal
Director, Pulmonary Function Laboratory, St. Michael’s Hospital
Director, HHT Program, St. Michael’s Hospital

Clinical Activities General Respiratory Medicine
Pulmonary Vascular Malformations
Hereditary Hemorrhagic Telangiectasia Clinic
Hepatopulmonary Clinic

Educational Activities
Examiner, Royal College of Physicians and Surgeons, Respirology

Current Local, Provincial, National and International Activities
Chair, HHT Foundation International, Scientific & Medical Advisory Board
Board Member, HHT Foundation International Scientific and Medical Advisory Board Board Member, Board of Directors, HHT Foundation International
International HHT Patient and Family Conference, Program Planning Committee

Research Interests Pulmonary arteriovenous malformations (diagnosis, treatment, outcomes)
Genetic diagnosis for Hereditary Hemorrhagic Telangiectasia
Mechanisms of development of vascular malformations in HHT Hepatopulmonary syndrome
COPD, effects of and air pollution

Current Grant Support
HHT Foundation International Grant November 2004-2005
Principal Investigator: Dr. Karen Swanson Co-investigator: Dr. Marie E. Faughnan
Mulitcenter study of Interferon á2B in Hereditary Hemorrhagic Telangiectasia $50,000 US

CIHR Proof of Principle 2003-2004
Principal Investigator: Dr. Michelle Letarte
Co-investigator: Dr. Marie E. Faughnan
A molecular diagnostic test for hereditary hemorrhagic telangiectasia $100,000

Ontario Thoracic Society 2002-2004
Principal Investigator: Dr. Marie E. Faughnan
Co-Investigator: Dr. F. Silverman Impact of Fine Particulate Pollution on Dynamic Hyperinflation in COPD Award: $26,919

Selected Recent Publications

Faughnan M.E., Thabet A., Mei-Zahav M., Colombo M., MacLusky I., Hyland R.H., Pugash R.A., Chait P., Henderson K., White R.I. Jr. Pulmonary arteriovenous malformations in children: outcomes of Transcatheter embolotherapy. (in press, Journal of Pediatrics)