Shereen Ezzat

Shereen Ezzat, MD, FRCPC, FACP
Senior Scientist Division of Applied Molecular Oncology
Ontario Cancer Institute (OCI)

Keywords: novel therapeutics, endocrine oncology, fibroblast growth factor receptors, transcriptional regulation, epigenetic control
Research Interests
Our lab studies the mechanisms of cancer development in hormone-producing glands (Endocrine tumors) including those arising from the thyroid, pituitary, endocrine pancreas, and adrenal glands.

We are interested in the mechanisms leading to the transcriptional and epigenetic regulation of tumor-derived growth and survival signals. Our focus is on members of the FGF family of receptor tyrosine kinases which play an important role in sporadic and familial forms of these diseases. Signaling emphasis is on non-classical heterophilic interactions with cell adhesion molecules.

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Related Webpages
Endocrine Oncology
Division of Applied Molecular Oncology