The Floras laboratory (Clinical Cardiovascular Physiology Laboratory at Toronto General Hospital) is recognized internationally for discoveries arising from its investigation of circulatory and cardiac control mechanisms in human health and disease. Its,particular emphasis is the role of the autonomic nervous system in heart failure, hypertension, renal failure, and sleep-related breathing disorders. Human research methods include microneurographic recording of post-ganglionic sympathetic nerve activity, frequency domain analysis of cardiovascular signals, cardiac and brachial ultrasound imaging and functional magnetic resonance brain imaging, Research findings appear in over 200 original publications and also are summarized and contextualized within a range of invited reviews, editorial commentaries, and book chapters. All are accessible through PubMed or via the web sites of the Toronto General Research Institute or the Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital. Looking forward, there is latitude to develop innovative projects in collaboration with clinician scientists in the disciplines of respiratory and sleep medicine, nephrology, coagulation, diabetes, women’s cardiovascular health, pregnancy, and exercise science plus opportunity to lead new initiatives involving device-based strategies for restoration of autonomic balance in heart failure.
Contact Name:
Dr. John S. Floras
Role:
Canada Research Chair in Integrative Cardiovascular Biology
Telephone:
416 586 8704
E-mail:
john.floras@utoronto.ca
Mailing Address:
Suite 1614, 600 University Avenue,
Toronto, ON M5G 1X5 Canada
